At first you need create zones, as much as you need, then please create players and associate each player with appropriate zones using Zones Tab. Your first multi room setup is ready to use!
The following articles will help you use Multi Room Audio Player:
How to connect sound card to amplifier
How to control Multi Room Audio Player remotely via web browser
How to use Multi Room Audio Player REST API
How to control Multi Room Audio Player via command line
How to create Jingles
How to schedule Jingles
How to generate playlist with periodic ads or announcements
Please use Help section to find more.